Yes, the Essequibo region is generally safe for tourists. However, as with traveling anywhere, it's important to take common-sense precautions to ensure your safety. This includes securing your belongings, traveling with reputable tour operators, and staying informed about the areas you plan to visit. Local guides are highly recommended for exploring remote areas and navigating the rivers safely.

The Essequibo region offers an array of local dishes that reflect its rich cultural heritage. Visitors should try the traditional Guyanese Pepperpot, a stew made from meat marinated in cassareep (a sauce made from cassava root) and spices. Other must-try dishes include cook-up rice, a one-pot dish with rice, beans, coconut milk, and meat or fish; and metemgee, a hearty soup with dumplings, vegetables, and salted meat or fish. For a taste of local drinks, try the refreshing coconut water directly from freshly cut coconuts, or the local rum.

Essequibo is a culturally diverse region with a mix of African, East Indian, Indigenous, and European influences. English is the official language, but you may also hear Creolese spoken locally. When interacting with residents, it's important to be respectful and courteous. Dress modestly when visiting local communities or religious sites. It's also appreciated when tourists show interest in local customs and participate in community activities. Always ask for permission before taking photographs of people or private property.